Wolfson Children's Hospital is part of Baptist Health multi-hospital system and adjacent to Baptist Medical Center Downtown. Wolfson Children's Hospital is one of the nation's top children's hospitals. Founded in 1955, Wolfson Children's Hospital is a 180-bed regional referral hospital serving children and is the only children's hospital in Northeast Florida and Southeast Georgia.

In addition to having comprehensive state-of-the-art clinical facilities, Wolfson Children's Hospital has extensive partnerships with primary care physicians and pediatric sub-specialists in Jacksonville at Nemours Children's Clinic, the University of Florida and Mayo Clinic Jacksonville. Wolfson Children's Hospital is a primary pediatric teaching facility for the University of Florida College of Pharmacy (Jacksonville Branch Campus), College of Medicine, College of Nursing and College of Allied Health. Nemours Children's Clinic also plays an integral role in the education of young professionals, allowing the opportunity to be involved with a diverse patient mix and nationally renowned faculty.